Mucuna pruriens in Parkinson’s disease: a double blind clinical and pharmacological study

@article{Katzenschlager2004MucunaPI,
  title={Mucuna pruriens in Parkinson’s disease: a double blind clinical and pharmacological study},
  author={R. Katzenschlager and A. Evans and A. Manson and P. Patsalos and N. Ratnaraj and H. Watt and L. Timmermann and R. Van der Giessen and A. Lees},
  journal={Journal of Neurology, Neurosurgery & Psychiatry},
  year={2004},
  volume={75},
  pages={1672 - 1677}
}
Background: The seed powder of the leguminous plant, Mucuna pruriens has long been used in traditional Ayurvedic Indian medicine for diseases including parkinsonism. We have assessed the clinical effects and levodopa (l-dopa) pharmacokinetics following two different doses of mucuna preparation and compared them with standard l-dopa/carbidopa (LD/CD). Methods: Eight Parkinson’s disease patients with a short duration l-dopa response and on period dyskinesias completed a randomised, controlled… Expand
219 Citations

Paper Mentions

Interventional Clinical Trial
In low-income areas worldwide, most patients with Parkinson's disease (PD) cannot afford long-term Levodopa therapy. A potential therapeutic option for them is the use of a legume… Expand
ConditionsParkinson's Disease
InterventionDrug, Other
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