Mucous membranepemphigoid in two half-sisters. The potential roles of autoantibodies to β4 integrin subunits and HLA-DQβ1*0301.

@article{Rabelo2014MucousMI,
  title={Mucous membranepemphigoid in two half-sisters. The potential roles of autoantibodies to β4 integrin subunits and HLA-DQβ1*0301.},
  author={Diogo Fabris Rabelo and Tegan Nguyen and Brooke Ann Caufield and Abdul Razzaque Ahmed},
  journal={Journal of dermatological case reports},
  year={2014},
  volume={8 1},
  pages={
          9-12
        }
}
BACKGROUND Mucous membrane pemphigoid (MMP) is a subepithelial autoimmune mucocutaneous disease. It most frequently affects the oral mucosa, followed by ocular and nasal mucosa, nasopharyngeal, anogenital, skin, laryngeal and esophageal mucosa. MAIN OBSERVATION Two half-sisters developed mucous membrane pemphigoid at approximately the same age. The older sister presented with primarily mucosal disease, while the younger had a more cutaneous disease. The histopathology demonstrated a… CONTINUE READING