Mucosal production of complement C3 and serum amyloid A is differentially regulated in different parts of the gastrointestinal tract during endotoxemia in mice

Abstract

The effect of endotoxemia and sepsis on mucosal production of the acute-phase proteins complement component C3 and serum amyloid A (SAA) was studied in mice. In addition, the role of the proinflammatory cytokines tumor necrosis factor-alpha, interleukin (EL)-Iβ, and IL-6 on mucosal C3 and SAA production was examined. Endotoxemia was induced by the… (More)
DOI: 10.1016/S1091-255X(98)80054-1

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