Mucosal mast cells mediate motor response induced by chronic oral exposure to ovalbumin in the rat gastrointestinal tract

@article{Traver2010MucosalMC,
  title={Mucosal mast cells mediate motor response induced by chronic oral exposure to ovalbumin in the rat gastrointestinal tract},
  author={E. Traver and R. Torres and F. de Mora and P. Vergara},
  journal={Neurogastroenterology & Motility},
  year={2010},
  volume={22}
}
  • E. Traver, R. Torres, +1 author P. Vergara
  • Published 2010
  • Medicine
  • Neurogastroenterology & Motility
  • Abstract  We previously demonstrated that oral chronic exposure to ovalbumin (OVA) causes intestinal hypermotility in Sprague‐Dawley rats. In this study, the objective was to determine the mechanism of action of OVA and the role of mucosal mast cells in the regulation of motor activity in this model. Rats were orally exposed to OVA during 6 weeks. Intestinal mucosal mast cells (IMMCs) were counted and rat mast cell protease II (RMCPII) measured in duodenum, jejunum, ileum and colon. Anti‐OVA… CONTINUE READING
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