Mucosal immunity and novel tuberculosis vaccine strategies: route of immunisation-determined T-cell homing to restricted lung mucosal compartments.

Abstract

Despite the use of bacille Calmette-Guérin (BCG) for almost a century, pulmonary tuberculosis (TB) continues to be a serious global health concern. Therefore, there has been a pressing need for the development of new booster vaccines to enhance existing BCG-induced immunity. Protection following mucosal intranasal immunisation with AdHu5Ag85A is associated… (More)
DOI: 10.1183/16000617.00002515

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Cite this paper

@article{Lai2015MucosalIA, title={Mucosal immunity and novel tuberculosis vaccine strategies: route of immunisation-determined T-cell homing to restricted lung mucosal compartments.}, author={Rocky Lai and S. Afkhami and Siamak Haddadi and Mangalakumari Jeyanathan and Zhou Xing}, journal={European respiratory review : an official journal of the European Respiratory Society}, year={2015}, volume={24 136}, pages={356-60} }