Mucosal defense against gastrointestinal nematodes: responses of mucosal mast cells and mouse mast cell protease 1 during primary strongyloides venezuelensis infection in FcRgamma-knockout mice.

@article{Onah2000MucosalDA,
  title={Mucosal defense against gastrointestinal nematodes: responses of mucosal mast cells and mouse mast cell protease 1 during primary strongyloides venezuelensis infection in FcRgamma-knockout mice.},
  author={Denis Nnabuike Onah and Fukumi Uchiyama and Y Nagakui and Masao Ono and Toshiyuki Takai and Yukifumi Nawa},
  journal={Infection and immunity},
  year={2000},
  volume={68 9},
  pages={4968-71}
}
A possible role for the gamma subunit of immunoglobulin Fc receptors (FcR) in mucosal defenses against intestinal nematode parasites was studied using age-matched FcRgamma-knockout (FcRgamma(-/-)) and wild-type (FcRgamma(+/+)) C57BL/6 mice. Mice were infected subcutaneously with 3,000 infective larvae of Strongyloides venezuelensis, and the degree of infection was monitored by daily fecal egg counts and adult worm recovery on days 8 and 13 postinfection. Mucosal mast cell (MMC) responses were… CONTINUE READING
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Glycoconjugates and host - parasite relationship in the mucosal defense against intestinal nematodes , p . 925 – 933

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