Mucosal cell proliferation activity of the gallbladder in children with anomalous arrangement of the pancreaticobiliary duct.

@article{Tokiwa1999MucosalCP,
  title={Mucosal cell proliferation activity of the gallbladder in children with anomalous arrangement of the pancreaticobiliary duct.},
  author={Kazuaki Tokiwa and Schu-ichi Ono and Naomi Iwai},
  journal={Journal of hepato-biliary-pancreatic surgery},
  year={1999},
  volume={6 3},
  pages={
          213-7
        }
}
Anomalous arrangement of the pancreaticobiliary duct (AAPBD) is an anatomical maljunction of the bile duct and the pancreatic duct that is frequently associated with gallbladder carcinoma. In patients with AAPBD, it has been postulated that pancreatic juice regurgitates into the biliary tree, and the mixture of refluxed pancreatic juice and stagnant bile juice acts as an irritant factor to the biliary tract epithelium, leading to chronic inflammation and metaplasia. Eventually these mucosal… CONTINUE READING
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