Mucosal-associated invariant T-cell function is modulated by programmed death-1 signaling in patients with active tuberculosis.

@article{Jiang2014MucosalassociatedIT,
  title={Mucosal-associated invariant T-cell function is modulated by programmed death-1 signaling in patients with active tuberculosis.},
  author={Jing Jiang and Xinjing Wang and Hongjuan An and Bingfen Yang and Zhihong Cao and Yanhua Liu and Jinwen Su and Fei Zhai and Ruo Jie Wang and Guangyu Zhang and Xiaoxing Cheng},
  journal={American journal of respiratory and critical care medicine},
  year={2014},
  volume={190 3},
  pages={
          329-39
        }
}
RATIONALE Mucosal-associated invariant T (MAIT) cells have been proven to play an important role in host defense against mycobacterial infection in animal infection models; however, the functional role of MAIT cells in patients with active tuberculosis (TB) is still largely unknown. OBJECTIVES To understand the clinical features and functions of MAIT cells in patients with active TB. METHODS MAIT cells were analyzed in patients with pulmonary TB, tuberculous pleurisy, and tuberculous… CONTINUE READING
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