Mucosal T-cell immunoregulation varies in early and late inflammatory bowel disease.

@article{Kugathasan2007MucosalTI,
  title={Mucosal T-cell immunoregulation varies in early and late inflammatory bowel disease.},
  author={Subra Kugathasan and Lawrence J. Saubermann and Linda G Smith and Dewei Kou and Jugoh Itoh and David G. Binion and Alan D. Levine and Richard S Blumberg and Claudio Fiocchi},
  journal={Gut},
  year={2007},
  volume={56 12},
  pages={1696-705}
}
BACKGROUND AND AIMS Crohn's disease is a life-long form of inflammatory bowel disease (IBD) mediated by mucosal immune abnormalities. Understanding of the pathogenesis is limited because it is based on data from adults with chronic Crohn's disease. We investigated mucosal T-cell immunoregulatory events in children with early Crohn's disease. METHODS Mucosal biopsies and T-cell clones were derived from children experiencing the first attack of Crohn's disease, children with long-standing Crohn… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 73 extracted citations

Similar Papers

Loading similar papers…