Mucosal Mast Cell Count Is Associated With Intestinal Permeability in Patients With Diarrhea Predominant Irritable Bowel Syndrome

@inproceedings{Lee2013MucosalMC,
  title={Mucosal Mast Cell Count Is Associated With Intestinal Permeability in Patients With Diarrhea Predominant Irritable Bowel Syndrome},
  author={H W Lee and Jung Ho Park and Dong Il Park and Hong Joo Kim and Yong Kyun Cho and Chong Il Sohn and Woo Kyu Jeon and Byung Ik Kim and Seoung Wan Chae},
  booktitle={Journal of neurogastroenterology and motility},
  year={2013}
}
BACKGROUND/AIMS Although mucosal mast cell tryptase is known to significantly increase intestinal permeability, the relationship between mucosal mast cells and intestinal permeability remains unclear. The objective of this study was to evaluate the correlation among intestinal permeability, tryptase activity and mucosal mast cell count. METHODS Rectal biopsies from 16 patients with diarrhea-predominant irritable bowel syndrome (IBS-D) and 7 normal subjects were assessed for tryptase activity… CONTINUE READING