Mucosal Macrophages in Intestinal Homeostasis and Inflammation

@inproceedings{Mowat2011MucosalMI,
  title={Mucosal Macrophages in Intestinal Homeostasis and Inflammation},
  author={Allan McI Mowat and Calum C Bain},
  booktitle={Journal of innate immunity},
  year={2011}
}
Intestinal macrophages are essential for local homeostasis and in keeping a balance between commensal microbiota and the host. However, they also play essential roles in inflammation and protective immunity, when they change from peaceful regulators to powerful aggressors. As a result, activated macrophages are important targets for treatment of inflammatory bowel diseases such as Crohn's disease. Until recently, the complexity and heterogeneity of intestinal macrophages have been… CONTINUE READING
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CX 3 CR 1 defines functionally distinct intestinal mononuclear phagocyte subsets which maintain their respective functions during homeostatic and inflammatory conditions

  • M Bogunovic, F Ginhoux, +11 authors M Merad
  • Eur J Immunol
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