Mucosal Interactions between Genetics, Diet, and Microbiome in Inflammatory Bowel Disease

  title={Mucosal Interactions between Genetics, Diet, and Microbiome in Inflammatory Bowel Disease},
  author={Abigail Raffner Basson and Ashley Trotter and Alexander Rodriguez-Palacios and Fabio Cominelli},
  journal={Frontiers in Immunology},
Numerous reviews have discussed gut microbiota composition changes during inflammatory bowel diseases (IBD), particularly Crohn’s disease (CD). However, most studies address the observed effects by focusing on studying the univariate connection between disease and dietary-induced alterations to gut microbiota composition. The possibility that these effects may reflect a number of other interconnected (i.e., pantropic) mechanisms, activated in parallel, particularly concerning various bacterial… 
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