Mucosal Damage and Neutropenia Are Required for Candida albicans Dissemination

Abstract

Candida albicans fungemia in cancer patients is thought to develop from initial gastrointestinal (GI) colonization with subsequent translocation into the bloodstream after administration of chemotherapy. It is unclear what components of the innate immune system are necessary for preventing C. albicans dissemination from the GI tract, but we have… (More)
DOI: 10.1371/journal.ppat.0040035

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