Mucormycosis (zygomycosis) in a heart-kidney transplant recipient: recovery after posaconazole therapy.

@article{Tobn2003MucormycosisI,
  title={Mucormycosis (zygomycosis) in a heart-kidney transplant recipient: recovery after posaconazole therapy.},
  author={{\'A}ngela M. Tob{\'o}n and M. V. de Arango and Dar{\'i}o Fern{\'a}ndez and {\'A}ngela Restrepo},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2003},
  volume={36 11},
  pages={1488-91}
}
We describe the case of a diabetic patient who developed a severe invasive fungal infection due to Rhizopus species postoperatively after a dual heart/kidney transplantation with subsequent intensive immunosuppressive therapy. No improvement was noted with amphotericin B (deoxycholate) therapy, but salvage treatment with the new azole antifungal posaconazole (200 mg orally 4 times daily) resulted in dramatic clinical improvement as early as 1 week after the initiation of therapy that continued… CONTINUE READING
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