Mucoepidermoid carcinoma of the parotid gland in childhood survivor of acute lymphoblastic leukemia with need of radiotherapy for treatment and review of the literature.

Abstract

Diagnosis of secondary malignancies began with the increasing survival in childhood cancer. Children treated for acute lymphoblastic leukemia (ALL) have an increased risk for developing mucoepidermoid carcinoma (MEC) of the parotid gland. The latent period ranges from 5 to 16 years. A 2 6/12-year-old girl was treated for pro-B ALL. Treatment included multidrug chemotherapy, prophylactic intrathecal methotrexate, and cranial radiotherapy. MEC of the left parotid gland was diagnosed at the age of 8 years, 3 years after completing treatment. She was treated with multiple surgery and radiotherapy. The authors aimed to emphasize the need for concern about second cancers of the parotid gland in children treated for ALL.

DOI: 10.3109/08880018.2012.673696

Cite this paper

@article{Tugcu2012MucoepidermoidCO, title={Mucoepidermoid carcinoma of the parotid gland in childhood survivor of acute lymphoblastic leukemia with need of radiotherapy for treatment and review of the literature.}, author={Deniz Tugcu and Ferhan Akici and Gonul Aydogan and Zafer Salcioglu and Arzu Akcay and Hulya Sen and Fulya Yaman Agaoglu and Emin Darendeliler and Yasemin Ozluk}, journal={Pediatric hematology and oncology}, year={2012}, volume={29 4}, pages={380-5} }