Mucociliary and long-term particle clearance in the airways of healthy nonsmoker subjects.
@article{Mller2004MucociliaryAL, title={Mucociliary and long-term particle clearance in the airways of healthy nonsmoker subjects.}, author={Winfried M{\"o}ller and Karl H{\"a}ussinger and Renate Winkler-Heil and Willi Stahlhofen and T. Meyer and Werner Hofmann and Joachim Prof Dr Heyder}, journal={Journal of applied physiology}, year={2004}, volume={97 6}, pages={ 2200-6 } }
Spherical monodisperse ferromagnetic iron oxide particles of 1.9-microm geometric and 4.2-microm aerodynamic diameter were inhaled by 13 healthy nonsmoking subjects using the shallow bolus technique. The bolus width was 100 ml, and the penetration front depth was 150 +/- 27 ml. The mean flow rate during inhalation and exhalation was 250 ml/s. The Fowler dead space and the phase 1 dead space of the airways were 282 +/- 49 and 164 +/- 34 ml, respectively. Deposition was below 20% without breath…
145 Citations
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