Mucoadhesive chitosan-coated cationic microemulsion of dexamethasone for ocular delivery: in vitro and in vivo evaluation.

@article{Kesavan2013MucoadhesiveCC,
  title={Mucoadhesive chitosan-coated cationic microemulsion of dexamethasone for ocular delivery: in vitro and in vivo evaluation.},
  author={Karthikeyan Kesavan and Shri Kant and Paras Nath Singh and Jayanta Kumar Pandit},
  journal={Current eye research},
  year={2013},
  volume={38 3},
  pages={342-52}
}
PURPOSE Dexamethasone (DXN) is an effective anti-inflammatory drug in the treatment of acute and chronic eye disease such as uveitis. However, its low aqueous solubility limits its clinical usefulness. The purpose of this study was to investigate the mucoadhesive chitosan-coated cationic microemulsions (CH-MEs) for ophthalmic delivery of DXN to treat… CONTINUE READING