Mucoadhesive and muco-penetrating delivery systems for eradication of Helicobacter pylori

  title={Mucoadhesive and muco-penetrating delivery systems for eradication of Helicobacter pylori},
  author={Saahil Arora and Gaurav Bisen and R. D. Budhiraja},
  journal={Asian Journal of Pharmaceutics},
Helicobacter pylori (H. pylori), the major culprit for peptic ulcer, has a unique way of survival in harsh acidic environment of the stomach by colonizing deep in the gastric mucosal layer. Failure of conventional therapies against H. pylori for complete eradication has major limitations like low residence time of delivery system in stomach, poor penetration of drug in gastric mucosa, acidic degradation of antibiotics, and development of antibiotics resistance. The poor penetration of… 

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