Mucidin resistance in yeast. Isolation, characterization and genetic analysis of nuclear and mitochondrial mucidin-resistant mutants of Saccharomyces cerevisiae.

@article{ubk1977MucidinRI,
  title={Mucidin resistance in yeast. Isolation, characterization and genetic analysis of nuclear and mitochondrial mucidin-resistant mutants of Saccharomyces cerevisiae.},
  author={J{\'u}lius {\vS}ub{\'i}k and Vlasta Kov{\'a}{\vc}ov{\'a} and G Tak{\'a}scov{\'a}},
  journal={European journal of biochemistry},
  year={1977},
  volume={73 1},
  pages={275-86}
}
Mutants of Saccharomyces cerevisiae resistant to the antibiotic mucidin, a specific inhibitor of electron transport between cytochrome b and c, were isolated and divided into three phenotypic groups, as follows. Class 1 mutants were cross-resistant to a variety of mitochondrial inhibitors and exhibited no resistance at the mitochondrial level. Class 2 mutants were specifically resistant to mucidin exhibiting resistance also at the level of isolated mitochondria. Biochemical studies indicated… CONTINUE READING

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