Much more from the chicken's egg than breakfast – a wonderful model system

  title={Much more from the chicken's egg than breakfast – a wonderful model system},
  author={Lewis Wolpert},
  journal={Mechanisms of Development},
  • L. Wolpert
  • Published 1 September 2004
  • Biology
  • Mechanisms of Development

Chicken embryo as a model for regenerative medicine.

  • C. Coleman
  • Biology
    Birth defects research. Part C, Embryo today : reviews
  • 2008
The chick offers a well-defined profile of intercellular and intracellular signaling pathways regulating the development of nearly every organ system in conjunction with great flexibility for chimeric and transgenic experiments.

Rediscovering the chick embryo as a model to study retinal development

A general overview of the chick as a developmental model focusing more specifically on its application to the study of eye development and the state of the art of the techniques that have made gene gain- and loss-of-function studies in this model a reality is provided.

Avian Embryonic Culture: A Perspective of In Ovo to Ex Ovo and In Vitro Studies

A panoramic view of the relationship among different cultivation platforms from in ovo studies to ex ovo as well as in vitro culture of cell lines with recent advances in the stem cell fields is provided.

From soil mechanics to chick development.

  • L. Wolpert
  • Biology
    The International journal of developmental biology
  • 2018
Here, I provide some recollections of my life, starting as a civil engineer in South Africa and how I gradually became interested in biology, particularly pattern formation. In retrospect, I think

Domestication and the comparative embryology of birds.

  • G. CorderoI. Werneburg
  • Biology
    Journal of experimental zoology. Part B, Molecular and developmental evolution
  • 2022
It is found that temporal variances for developmental events are generally uniform across a consensus chronological sequence for birds, and developmental trajectories for chicken and other model species appear to be highly similar.

A Novel Fully Automated Incubation, Manipulation and Documentation System for the Avian Embryogenesis

An avian egg incubator with a modular lid system comprising a glass window with condensation prevention and a parallel access for manipulation and the influence of light exposure as well as turning speed and frequency on the embryo survival rate for optimized culture conditions is presented.

A new take on an old story: chick limb organ culture for skeletal niche development and regenerative medicine evaluation.

The evolution of the chick limb organ culture system is detailed and recent innovative developments and emerging techniques and technologies applied to these models that are aiding the understanding of skeletal developmental and regenerative medicine research and application are presented.

Applications of Tol2 transposon-mediated gene transfer for stable integration and conditional expression of electroporated genes in chicken embryos

The electroporation technique using chickens has provided numerous novel insights into the understanding of early development in vertebrates, making the chicken a unique model animal.



The Development of the Chick

  • B.
  • Biology
  • 1909
The chick has played a very large and undeserved part in the history of embryology from the time of Harvey, Caspar Friedrich Wolff and earlier, through all the years during which Pander and Carl Ernst von Baer devoted themselves to its study, down to to-day.

The Principles of Development

This chapter discusses the development of the Drosophila body plan, as well as life cycles and experimental techniques, and the role of the nervous system in this development.

The Elements of Experimental Embryology

THIS work is a rather surprising addition to the Cambridge Comparative Physiology series—surprising partly because it is twice as heavy as any of the earlier members of the series, and partly because

Development of the eye of the chick embryo.

Experimental analysis of eye development has revealed an intimate relationship between invagination of the lens and optic cup, and the effects of inhibitory drugs suggest the involvement at least in part of a contractile mechanism during optic cup formation.

A History of Embryology

LOVERS of Tristram Shandy will remember that passage in which Sterne gives a cut of his ironic whip at the learned Catholic doctors of the Sorbonne, who in their zeal to save souls had given a very

Organisers and Genes

Genetical results have great practical value in the fields of agriculture, eugenics, and evolution, even if they are not applied to the study of development, but genetics will remain a somewhat isolated branch of biology until this is done.