Mu-opioid receptor trafficking on inhibitory synapses in the rat brainstem.

  title={Mu-opioid receptor trafficking on inhibitory synapses in the rat brainstem.},
  author={Kirsteen N Browning and Alexander E. Kalyuzhny and R Alberto Travagli},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={24 33},
Whole-cell recordings were made from identified gastric-projecting rat dorsal motor nucleus of the vagus (DMV) neurons. The amplitude of evoked IPSCs (eIPSCs) was unaffected by perfusion with met-enkephalin (ME) or by mu-, delta-, or kappa-opioid receptor selective agonists, namely D-Ala2-N-Me-Phe4-Glycol5-enkephalin (DAMGO), cyclic [D-Pen2-D-Pen5]-enkephalin, or trans-3,4-dichloro-N-methyl-N-[2-(1-pyrolytinil)-cyclohexyl]-benzeneacetamide methane sulfonate (U50,488), respectively. Brief… CONTINUE READING


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