MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain.

@article{He2014MrgCAA,
  title={MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain.},
  author={Shao-Qiu He and Zhe Li and Yu-Xia Chu and Liang Han and Qian Xu and Man Li and Fei Yang and Jingjing Liu and Zongxiang Tang and Yun Song Wang and Niyada Hin and Takashi Tsukamoto and Barbara S Slusher and Vinod Tiwari and Ronen Shechter and Feng Wei and Srinivasa N Raja and Xinzhong Dong and Yun Guan},
  journal={Pain},
  year={2014},
  volume={155 3},
  pages={534-44}
}
Chronic neuropathic pain is often refractory to current pharmacotherapies. The rodent Mas-related G-protein-coupled receptor subtype C (MrgC) shares substantial homogeneity with its human homologue, MrgX1, and is located specifically in small-diameter dorsal root ganglion neurons. However, evidence regarding the role of MrgC in chronic pain conditions has been disparate and inconsistent. Accordingly, the therapeutic value of MrgX1 as a target for pain treatment in humans remains uncertain. Here… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS
9 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…