MreB filaments align along greatest principal membrane curvature to orient cell wall synthesis

@inproceedings{Hussain2018MreBFA,
  title={MreB filaments align along greatest principal membrane curvature to orient cell wall synthesis},
  author={Saman Hussain and Carl N Wivagg and Piotr Szwedziak and Felix Wong and Kaitlin Schaefer and Thierry Izor{\'e} and Lars D Renner and Matthew J Holmes and Yingjie Sun and Alexandre W Bisson-Filho and Suzanne Walker and Ariel Amir and Jan L{\"o}we and Ethan C Garner},
  booktitle={eLife},
  year={2018}
}
MreB is essential for rod shape in many bacteria. Membrane-associated MreB filaments move around the rod circumference, helping to insert cell wall in the radial direction to reinforce rod shape. To understand how oriented MreB motion arises, we altered the shape of Bacillus subtilis. MreB motion is isotropic in round cells, and orientation is restored when rod shape is externally imposed. Stationary filaments orient within protoplasts, and purified MreB tubulates liposomes in vitro, orienting… CONTINUE READING