Moxonidine: a review

  title={Moxonidine: a review},
  author={S N Morris and J H Reid},
  journal={Journal of Human Hypertension},
Moxonidine is an imidazoline compound which acts on I1 imidazoline ‘receptors’ in the central nervous system to reduce blood pressure. This novel mechanism of action is claimed to lead to fewer adverse effects than the older centrally-acting agents such as clonidine. In this review we examine the drug’s pharmacology, clinical pharmacokinetics, efficacy as an antihypertensive agent including comparative studies with pre-existing drugs, and adverse effect profile. With a growing number of… CONTINUE READING