Moving toward earlier treatment of multiple sclerosis: Findings from a decade of clinical trials and implications for clinical practice.


The first clinical presentation of multiple sclerosis (MS) is usually a single episode of typical symptoms and signs and is designated a "first clinical demyelinating event" (FCDE) or a "clinically isolated syndrome". Patients with an FCDE who show 'silent' magnetic resonance imaging lesions are at high risk of further clinical events and therefore of… (More)
DOI: 10.1016/j.msard.2013.07.001


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