Moving to nucleic acid-based detection of genital Chlamydia trachomatis

  title={Moving to nucleic acid-based detection of genital Chlamydia trachomatis},
  author={Cheuk Yan William Tong and Harry Mallinson},
  journal={Expert Review of Molecular Diagnostics},
  pages={257 - 266}
  • C. Tong, H. Mallinson
  • Published 1 May 2002
  • Medicine, Biology
  • Expert Review of Molecular Diagnostics
Laboratory diagnosis of the bacterium Chlamydia trachomatis has gone through a complete phase of evolution since it was first identified as a significant cause of sexually transmitted infection. As a fragile, obligatory intracellular organism, it was initially only grown in eggs. Subsequently, diagnosis relied on culture in continuous cell lines. To address the limitations of culture, immunological methods were developed and direct antigen detection using enzyme immunoassay and… 
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