Moving molecular targeted drug therapy towards personalized medicine: issues related to clinical trial design.

Abstract

With the event of new Molecular targets, clinical trial design requirements to perform these trials are changing. This paper discusses some of the considerations that need to be taken into account when designing a trial, including those trials that assess combinations of targets.

DOI: 10.1016/j.molonc.2012.01.009

Cite this paper

@article{Verweij2012MovingMT, title={Moving molecular targeted drug therapy towards personalized medicine: issues related to clinical trial design.}, author={Jaap Verweij and Maja J. A. de Jonge and Ferry A. L. M. Eskens and Stefan Sleijfer}, journal={Molecular oncology}, year={2012}, volume={6 2}, pages={196-203} }