Movement related potentials and oscillatory activities in the human internal globus pallidus during voluntary movements

  title={Movement related potentials and oscillatory activities in the human internal globus pallidus during voluntary movements},
  author={Eric W. Tsang and Clement Hamani and Elena Moro and Filomena Mazzella and Andres M. Lozano and Mojgan Hodaie and I J Yeh and Robert Chen},
  journal={Journal of Neurology, Neurosurgery \& Psychiatry},
  pages={91 - 97}
Objective To study internal globus pallidus (GPi) activities and the interactions among the bilateral GPi and motor cortical areas during voluntary movements. Methods Five patients with cervical dystonia who underwent bilateral GPi deep brain stimulation (DBS) were studied. Local field potentials from the GPi DBS electrodes and EEG were recorded while the patients performed externally triggered and self-initiated right wrist movements. Results Movement related potentials were recorded at the… 
Time-course of coherence in the human basal ganglia during voluntary movements
A mathematical model involving coupled neural oscillators provides a possible explanation for how inter-regional coupling takes place in dystonia and Parkinson’s disease patients.
Globus pallidus internus oscillatory activity is related to movement speed
An increase in movement speed changes the power of GPi oscillations by means of a reduction of the activity in the low beta band and an elevation of activity inThe gamma band.
Prominent 5–18 Hz oscillations in the pallidal-thalamic circuit in secondary dystonia
If the 5-18 Hz rhythm is related to dystonia, attempted movements of dystonic muscles would result in less attenuation of this 5–18 Hz oscillation compared to normal movements.
The Functional Significance of Oscillatory Activities in the Basal Ganglia and Pedunculopontine Nucleus Region in Parkinson’s Disease and Dystonia
This work recorded STN LFP from PD patients and subsequently applied the intrinsic STN theta, beta, and gamma frequencies through DBS to study their effects on PD motor signs, and simultaneously recorded movement-related activities from the GPi and the BG.
Parkinsonian Beta Dynamics during Rest and Movement in the Dorsal Pallidum and Subthalamic Nucleus
Comparing beta power in the STN and GPi during rest and movement in 37 people with PD undergoing DBS found that beta dynamics differed across basal ganglia nuclei, which could point to the GPi as a potentially effective target for beta-based adaptive DBS.
Finely-tuned gamma oscillations: Spectral characteristics and links to dyskinesia
Power Modulations of ECoG Alpha/Beta and Gamma Bands Correlate With Time-Derivative of Force During Hand Grasp
The fluctuations of HFB-ERS primarily, and of LFB-ERD to a lesser extent, correlated with the time-course of the first time-derivative of force (yank), rather than with force itself, the first study that establishes such a correlation.


Local field potentials and oscillatory activity of the internal globus pallidus in myoclonus–dystonia
Local field potential activities in the globus pallidus internus (GPi) from two genetically proven M–D patients are investigated and recordings of the GPi show that the low‐frequency band previously described in dystonia is also involved in the dySTONia plus syndrome M-D.
Involvement of the Basal Ganglia and Cerebellar Motor Pathways in the Preparation of Self-Initiated and Externally Triggered Movements in Humans
The subthalamic nucleus (STN) is part of the cortico-basal ganglia (BG)–thalamocortical circuit, whereas the ventral lateral nucleus of the thalamus (VL) is a relay nucleus in the
The sensory and motor representation of synchronized oscillations in the globus pallidus in patients with primary dystonia.
In 15 patients with primary dystonia who were treated with bilateral chronic pallidal stimulation, the sensorimotor modulation of the oscillatory local field potentials (LFPs) recorded from the pallidal electrodes were investigated and correlated with the surface electromyograms in the affected muscles.
Movement‐related synchronization of gamma activity is lateralized in patients with dystonia
The presence of a lateralized movement‐related increase in gamma activity in the BG of patients with dystonia, similar to that recorded in patients with treated PD, suggests that this may be a residual feature of normal BG function, and provides further support for functional distinctions between BG oscillatory activities of different frequency.
Gamma activity and reactivity in human thalamic local field potentials
An oscillatory activity with similar spectral characteristics and motor reactivity in the human thalamus is demonstrated, strengthened by the finding that fast thalamic oscillations were lost in untreated parkinsonian patients, paralleling the behaviour of this activity in the basal ganglia.
Movement-related cortical potentials.
  • M. Hallett
  • Biology, Psychology
    Electromyography and clinical neurophysiology
  • 1994
Movement-related cortical potentials represent averaged electroencephalographic activity before and after a voluntary movement and appear to represent feedback from the movement and may originate, in part, from the supplementary motor area.
Modulation of beta oscillations in the subthalamic area during motor imagery in Parkinson's disease.
The data suggest that the activity in the region of the human STN indexed by the ERD during movement is related to the feedforward organization of movement and is relatively independent of peripheral feedback.