Movement of replicating DNA through a stationary replisome.

@article{Lemon2000MovementOR,
  title={Movement of replicating DNA through a stationary replisome.},
  author={Katherine P. Lemon and Alan D Grossman},
  journal={Molecular cell},
  year={2000},
  volume={6 6},
  pages={1321-30}
}
We found that DNA is replicated at a central stationary polymerase, and each replicated region moves away from the replisome. In Bacillus subtilis, DNA polymerase is predominantly located at or near midcell. When replication was blocked in a specific chromosomal region, that region was centrally located with DNA polymerase. Upon release of the block, each copy of the duplicated region was located toward opposite cell poles, away from the central replisome. In a roughly synchronous population of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 100 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 42 references

Dynamic organization required for normal chromosome segregation as well as the initiation of chromosomal DNA in Escherichia coli

  • K. Ireton, N. W. Gunther, Y. Yamaichi, S. Hiraga
  • Genes Dev . J . Bacteriol .
  • 2000

A Bacillus subtilis gene - encoding protein ho - served scheme from bacteria to vertebrates ?

  • S. Moriya, E. Tsujikawa, A. K. Hassan, K. Asai, T. Kodama, T. Hirano
  • Genes Dev .
  • 1999

The Caulobacter crescentus fluorescent protein

  • M. Ormo, A. B. Cubitt, +4 authors L. Shapiro
  • Science
  • 1999

The organization of replication and transcription

  • P. R. Cook
  • Stringent Response Experiments Science
  • 1999
1 Excerpt

Similar Papers

Loading similar papers…