Movement of Bax from the Cytosol to Mitochondria during Apoptosis

@article{Wolter1997MovementOB,
  title={Movement of Bax from the Cytosol to Mitochondria during Apoptosis },
  author={Keith G. Wolter and Y T Hsu and Carolyn L. Smith and Amotz Nechushtan and Xu-Guang Xi and Richard J Youle},
  journal={The Journal of Cell Biology},
  year={1997},
  volume={139},
  pages={1281 - 1292}
}
Bax, a member of the Bcl-2 protein family, accelerates apoptosis by an unknown mechanism. Bax has been recently reported to be an integral membrane protein associated with organelles or bound to organelles by Bcl-2 or a soluble protein found in the cytosol. To explore Bcl-2 family member localization in living cells, the green fluorescent protein (GFP) was fused to the NH2 termini of Bax, Bcl-2, and Bcl-XL. Confocal microscopy performed on living Cos-7 kidney epithelial cells and L929… CONTINUE READING
Highly Influential
This paper has highly influenced 45 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
694 Citations
41 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 694 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 41 references

Similar Papers

Loading similar papers…