Movement chunking during sequence learning is a dopamine-dependant process: a study conducted in Parkinson’s disease

@article{Tremblay2010MovementCD,
  title={Movement chunking during sequence learning is a dopamine-dependant process: a study conducted in Parkinson’s disease},
  author={Pierre-Luc Gilbert Tremblay and Marc-Andre Bedard and Dominic Langlois and Pierre J. Blanchet and Martin Lemay and Maxime Parent},
  journal={Experimental Brain Research},
  year={2010},
  volume={205},
  pages={375-385}
}
Chunking of single movements into integrated sequences has been described during motor learning, and we have recently demonstrated that this process involves a dopamine-dependant mechanism in animal (Levesque et al. in Exp Brain Res 182:499–508, 2007; Tremblay et al. in Behav Brain Res 198:231–239, 2009). However, there is no such evidence in human. The aim of the present study was to assess this question in Parkinson’s disease (PD), a neurological condition known for its dopamine depletion in… CONTINUE READING

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