Mouse transferrin receptor 1 is the cell entry receptor for mouse mammary tumor virus.

@article{Ross2002MouseTR,
  title={Mouse transferrin receptor 1 is the cell entry receptor for mouse mammary tumor virus.},
  author={Susan R Ross and Jason J Schofield and Christine J Farr and Maja Bucan},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2002},
  volume={99 19},
  pages={
          12386-90
        }
}
Enveloped viruses enter cells by binding to their entry receptors and fusing with the membrane at the cell surface or after trafficking through acidic endosomal compartments. Species-specific virus tropism is usually determined by these entry receptors. Because mouse mammary tumor virus (MMTV) is unable to infect Chinese hamster cells, we used phenotypic screening of the T31 mouse/hamster radiation hybrid panel to map the MMTV cell entry receptor gene and subsequently found that it is… CONTINUE READING

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