Mouse transcriptome: Neutral evolution of ‘non-coding’ complementary DNAs (reply)

@article{Hyashizaki2004MouseTN,
  title={Mouse transcriptome: Neutral evolution of ‘non-coding’ complementary DNAs (reply)},
  author={Yoshihide Hyashizaki},
  journal={Nature},
  year={2004},
  volume={431},
  pages={-}
}
Wang et al. challenge our suggestion that almost half of the 33,407 representative putative full-length cDNAs identified by RIKEN are probably non-coding RNAs. The challenge is based on bioinformatic analyses showing that the level of conservation of these sequences is no greater than that observed for intergenic sequences, and less than that observed in a control set of documented ncRNAs.