Mouse thymus dendritic cells: kinetics of development and changes in surface markers during maturation.

@article{Wu1995MouseTD,
  title={Mouse thymus dendritic cells: kinetics of development and changes in surface markers during maturation.},
  author={Li Wu and David Vremec and Carlos Ardav{\'i}n and Ken D Winkel and G R Suess and Harry M Georgiou and Eugene Maraskovsky and Wendy Cook and Ken D Shortman},
  journal={European journal of immunology},
  year={1995},
  volume={25 2},
  pages={418-25}
}
The early thymus precursor population of adult mice has the capacity to generate T cells, B cells and dendritic cells (DC). These precursors were injected into the thymus of irradiated recipients in order to follow the kinetics of thymic DC development. The resultant cohort of T-lineage cells developing in the thymus was accompanied by a parallel cohort of DC, present at 10(3)-fold lower frequency. The intrathymic lifespan of these DC was as short as that of T-lineage thymocytes. As the thymic… CONTINUE READING

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