Mouse submandibular gland morphogenesis: a paradigm for embryonic signal processing.

@article{Melnick2000MouseSG,
  title={Mouse submandibular gland morphogenesis: a paradigm for embryonic signal processing.},
  author={Michael M Melnick and Tina Jaskoll},
  journal={Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists},
  year={2000},
  volume={11 2},
  pages={199-215}
}
Signal processing is the sine qua non of embryogenesis. At its core, any single signal transduction pathway may be understood as classic Information Theory, adapted as an open system such that, because of networking, the "receiver" is presented with more information than was initially signaled by the "source". Over 40 years ago, Waddington presented his "Epigenetic Landscape" as a metaphor for the hierarchical nature of embryogenesis. Mathematically, Waddington's landscape may be modeled as a… CONTINUE READING

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