Mouse strain differences in the induction of micronuclei by polycyclic aromatic hydrocarbons.

@article{Sato1987MouseSD,
  title={Mouse strain differences in the induction of micronuclei by polycyclic aromatic hydrocarbons.},
  author={Seiichi Sato and Hiroyuki Kitajima and Shota Konishi and Hisao Takizawa and Naoki Inui},
  journal={Mutation research},
  year={1987},
  volume={192 3},
  pages={185-9}
}
The frequency of micronucleated erythrocytes (MNE) in 3 inbred mouse strains and 2 of their hybrids (C57BL/6, BALB/c, DBA/2, BDF1 and CDF1) were examined after polycyclic aromatic hydrocarbons (PAHs; 7,12-dimethylbenz[a]anthracene (DMBA), 3-methylcholanthrene (3-MC), benzo[a]pyrene (BaP), benzo[e]pyrene (BeP) and anthracene (ANT] were injected i.p. PAHs are thought to form active metabolites after being administered to mammals. In mouse strains with inducible PAH activating enzymes, such as… CONTINUE READING