Mouse pharmacological models of cognitive disruption relevant to schizophrenia

@article{Young2012MousePM,
  title={Mouse pharmacological models of cognitive disruption relevant to schizophrenia},
  author={Jared W Young and Susan B. Powell and Mark A. Geyer},
  journal={Neuropharmacology},
  year={2012},
  volume={62},
  pages={1381-1390}
}
Schizophrenia is a debilitating cognitive disorder. The link between cognitive debilitation and functional outcome in patients with schizophrenia has prompted research to develop procognitive therapies. It is hoped that by improving cognition in these patients, their functional outcome will also improve. Although no established treatments exist as yet, progress has been made toward understanding how to evaluate putative compounds in the clinic. Genetic mouse models and pharmacological rat… CONTINUE READING

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