Mouse peptidoglycan recognition protein PGLYRP-1 plays a role in the host innate immune response against Listeria monocytogenes infection.

@article{Osanai2011MousePR,
  title={Mouse peptidoglycan recognition protein PGLYRP-1 plays a role in the host innate immune response against Listeria monocytogenes infection.},
  author={Arihiro Osanai and Hiroshi Sashinami and Krisana Asano and Sheng-Jun Li and Dong-Liang Hu and Akio Nakane},
  journal={Infection and immunity},
  year={2011},
  volume={79 2},
  pages={
          858-66
        }
}
The role of mouse peptidoglycan recognition protein PGLYRP-1 in innate immunity against Listeria monocytogenes infection was studied. The recombinant mouse PGLYRP-1 and a polyclonal antibody specific to PGLYRP-1 were prepared. The mouse PGLYRP-1 showed antibacterial activities against L. monocytogenes and other Gram-positive bacteria. PGLYRP-1 mRNA expression was induced in the spleens and livers of mice infected with L. monocytogenes. The viable bacterial number increased, and the production… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-6 of 6 citations