Mouse oocyte control of granulosa cell development and function: paracrine regulation of cumulus cell metabolism.

@article{Su2009MouseOC,
  title={Mouse oocyte control of granulosa cell development and function: paracrine regulation of cumulus cell metabolism.},
  author={You-Qiang Su and Koji Sugiura and John J. Eppig},
  journal={Seminars in reproductive medicine},
  year={2009},
  volume={27 1},
  pages={32-42}
}
Bidirectional communication between oocytes and the companion granulosa cells is essential for the development and functions of both compartments. Oocytes are deficient in their ability to transport certain amino acids and in carrying out glycolysis and cholesterol biosynthesis. Cumulus cells must provide them with the specific amino acids and the products… CONTINUE READING