Mouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathway.

@article{Yoshimura1996MouseOM,
  title={Mouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathway.},
  author={Akihiko Yoshimura and Masatoshi Ichihara and Ichiko Kinjyo and Mariko Moriyama and Neal G. Copeland and Debra J. Gilbert and Nancy A. Jenkins and Tomoko Hara and Atsushi Miyajima},
  journal={The EMBO journal},
  year={1996},
  volume={15 5},
  pages={1055-63}
}
Oncostatin M (OSM) is a member of the interleukin-6 (IL6)-related cytokine subfamily that includes IL6, IL11, leukemia inhibitory factor (LIF), ciliary neurotrophic factor and cardiotrophin-1. While human OSM has been characterized and the bovine OSM gene was recently cloned, the murine counterpart had not been identified. Here we describe molecular cloning of murine OSM as an immediate early gene induced by a subset of cytokines including IL2, IL3 and erythropoietin (EPO) in myeloid and… CONTINUE READING