Mouse neuroinvasive phenotype of West Nile virus strains varies depending upon virus genotype.

@article{Beasley2002MouseNP,
  title={Mouse neuroinvasive phenotype of West Nile virus strains varies depending upon virus genotype.},
  author={David Beasley and Li Li and Miguel T Suderman and Alan D. T. Barrett},
  journal={Virology},
  year={2002},
  volume={296 1},
  pages={17-23}
}
Despite recent advances in the genetics of West Nile (WN) virus, relatively little is known about the molecular basis of virulence of this virus. In particular, although the genotype of the WN virus strain that was recently introduced into North America has been determined, there have been few experimental studies on the virulence phenotype of the virus. We compared genetic and neurovirulence properties of 19 strains of WN virus, including 2 from North America, and observed significant… CONTINUE READING
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