Mouse models of efficient and inefficient anti-tumor immunity, with emphasis on minimal residual disease and tumor escape

@article{Egorov2005MouseMO,
  title={Mouse models of efficient and inefficient anti-tumor immunity, with emphasis on minimal residual disease and tumor escape},
  author={Igor K. Egorov},
  journal={Cancer Immunology, Immunotherapy},
  year={2005},
  volume={55},
  pages={1-22}
}
Tumor escape from the host immune response remains the major problem holding the development of immunotherapies for cancer. In this review, congenic mouse lines are discussed that differ dramatically in their ability to respond to tumors tested and, thereby, to survive or to succumb to the tumor and/or its metastases. This ability is under the control of… CONTINUE READING