Mouse models of ALS: Past, present and future

  title={Mouse models of ALS: Past, present and future},
  author={C. Lutz},
  journal={Brain Research},
  • C. Lutz
  • Published 2018
  • Biology, Medicine
  • Brain Research
  • Genome sequencing of both sporadic and familial patients of Amyotrophic Lateral Sclerosis (ALS) has led to the identification of new genes that are both contributing and causative in the disease. This gene discovery has come at an unprecedented rate, and much of it in recent years. Knowledge of these genetic mutations provides us with opportunities to uncover new and related mechanisms, increasing our understanding of the disease and bringing us closer to defined therapies for patients. Mouse… CONTINUE READING
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