Mouse models of ALS: Past, present and future

@article{Lutz2018MouseMO,
  title={Mouse models of ALS: Past, present and future},
  author={Cathleen Lutz},
  journal={Brain Research},
  year={2018},
  volume={1693},
  pages={1-10}
}
  • C. Lutz
  • Published 1 August 2018
  • Biology, Medicine
  • Brain Research
Genome sequencing of both sporadic and familial patients of Amyotrophic Lateral Sclerosis (ALS) has led to the identification of new genes that are both contributing and causative in the disease. This gene discovery has come at an unprecedented rate, and much of it in recent years. Knowledge of these genetic mutations provides us with opportunities to uncover new and related mechanisms, increasing our understanding of the disease and bringing us closer to defined therapies for patients. Mouse… Expand
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