Mouse models in the study of the Ets family of transcription factors

@article{Bartel2000MouseMI,
  title={Mouse models in the study of the Ets family of transcription factors},
  author={Frank O Bartel and Tsukasa Higuchi and Demetri D. Spyropoulos},
  journal={Oncogene},
  year={2000},
  volume={19},
  pages={6443-6454}
}
The Ets family of transcription factors is one of a growing number of master regulators of development. This family was originally defined by the presence of a conserved DNA binding domain, the Ets domain. To date, nearly 30 members of this family have been identified and implicated in a wide range of physiological and pathological processes. Despite the likely importance of Ets-family members, each of their precise roles has not been delineated. Herein, we describe the elucidation of essential… CONTINUE READING
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