Mouse models in male fertility research.

  title={Mouse models in male fertility research.},
  author={Duangporn Jamsai and Moira K O'Bryan},
  journal={Asian journal of andrology},
  volume={13 1},
Limited knowledge of the genetic causes of male infertility has resulted in few treatment and targeted therapeutic options. Although the ideal approach to identify infertility causing mutations is to conduct studies in the human population, this approach has progressed slowly due to the limitations described herein. Given the complexity of male fertility, the entire process cannot be modeled in vitro. As such, animal models, in particular mouse models, provide a valuable alternative for gene… CONTINUE READING

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