Mouse models for human familial adenomatous polyposis.


Colorectal cancer (CRC) is the second most frequent type of cancer in the Western hemisphere. In the United States alone, it is estimated that 150 000 new cases are detected every year and more than 65 000 patients die from complications associated with this cancer. Identification of genes implicated in the initiation and progression of colorectal cancer in… (More)


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@article{Kucherlapati2001MouseMF, title={Mouse models for human familial adenomatous polyposis.}, author={Raju Kucherlapati and Derek Lin and Winfried Edelmann}, journal={Seminars in cancer biology}, year={2001}, volume={11 3}, pages={219-25} }