Mouse models for atherosclerosis and pharmaceutical modifiers.

@article{Zadelaar2007MouseMF,
  title={Mouse models for atherosclerosis and pharmaceutical modifiers.},
  author={S. Zadelaar and R. Kleemann and L. Verschuren and J. de Vries-van der Weij and J. V. D. van der Hoorn and H. Princen and T. Kooistra},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2007},
  volume={27 8},
  pages={
          1706-21
        }
}
Atherosclerosis is a multifactorial highly-complex disease with numerous etiologies that work synergistically to promote lesion development. The ability to develop preventive and ameliorative treatments will depend on animal models that mimic the human subject metabolically and pathophysiologically and will develop lesions comparable to those in humans. The mouse is the most useful, economic, and valid model for studying atherosclerosis and exploring effective therapeutic approaches. Among the… Expand
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