Mouse micronucleus assay as a surrogate to assess genotoxic potential of arsenic at its human reference dose.

@article{Khan2013MouseMA,
  title={Mouse micronucleus assay as a surrogate to assess genotoxic potential of arsenic at its human reference dose.},
  author={Parimal K. Khan and Vibudh P. Kesari and Amod Kumar},
  journal={Chemosphere},
  year={2013},
  volume={90 3},
  pages={993-7}
}
Exposure to high contents of arsenic (a genotoxic carcinogen) in humans through drinking water is one of the most serious concerns in many parts of the world including India. The United States Environmental Protection Agency (USEPA) has recommended a permissible limit of daily exposure in humans to arsenic as its reference dose (0.3 μg kg(-1) d(-1)) with almost no likelihood of any adverse effect. The present work was a quantitative assessment of the genotoxic potential of arsenic at the… CONTINUE READING
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