Mouse mammary tumor biology: a short history.

  title={Mouse mammary tumor biology: a short history.},
  author={Robert Cardiff and Nicholas Kenney},
  journal={Advances in cancer research},
For over a century, mouse mammary tumor biology and the associated Mouse mammary tumor virus (MMTV) have served as the foundation for experimental cancer research, in general, and, in particular, experimental breast cancer research. Spontaneous mouse mammary tumors were the basis for studies of the natural history of neoplasia, oncogenic viruses, host responses, endocrinology, and neoplastic progression. However, lacking formal proof of a human mammary tumor virus, the preeminence of the mouse… CONTINUE READING


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