Mouse macrophage development in the absence of the common gamma chain: defining receptor complexes responsible for IL-4 and IL-13 signaling.

@article{Andersson1997MouseMD,
  title={Mouse macrophage development in the absence of the common gamma chain: defining receptor complexes responsible for IL-4 and IL-13 signaling.},
  author={Asa Andersson and Susanne M. Grunewald and Albert Duschl and Alain Fischer and J P Disanto},
  journal={European journal of immunology},
  year={1997},
  volume={27 7},
  pages={1762-8}
}
The common gamma chain (gamma c) forms a critical component of the receptors for interleukins (IL)-2, IL-4, IL-7, IL-9, and IL-15. We analyzed gamma c-deficient mice to define a role for gamma c signaling in the development and function of the macrophage lineage. No major differences in absolute cell numbers, cell surface phenotype, or in vitro function of… CONTINUE READING